Today I discovered that all RGR emulated games do not want to work anymore. Arcade, PSX, NES, Atari 2600...it doesn't matter which console or game. The emulator itself loads just fine and the games are working with sound and whatnot. But the controls do not work, and I cannot bring up any options screen for the emulator itself (such as hitting Esc on the MAME games if you want to change control inputs).
The weird thing is they were all working fine yesterday. I re-installed the plugin today, but it did no good.

Wow, okay, so now they decided to work again. I'm not exactly sure what was going on, but it seems to be fixed.

I have the same problem on at least the GBA, SNES, and NES emulators, but my PlayStation emulator works fine.  Using Firefox, Windows 10, no special antivirus, and the latest version of RGR.

ZanderShadowbane :  
Are you using Mednafen for all of those systems, or just PSX? I can't imagine why it would work for one system but not the others, unless you're using a different emulator for the systems giving you trouble. 

VisualBoyAdvance and Mednafen don't work on gameboy games.  ZSnes and Mednafen don't work for SNES but Flash does.  FCEUX, Mednafen and Mess don't work for NES games, Java won't load (Not surprising) but again Flash does work.  Gens, Mednafen, and Mess don't work for Genesis Games.  1964 and Mupen64Plus don't work on N64.  Mednafen works for PS1 but in a limited capacity, when I start the emulator I can load a save-state, but am unable to create or load a save-state, change controls, or check out help.  I'm able to use it because I had configured PSX to use a USB controller rather than my keyboard.  Also of note is that sometimes a button will respond once and you can get past the menu but that's only happened twice, and it doesn't seem to work afterwords. 

One of the Log readings is:
23:17:30.728 - Vizzed plugin init script starting
23:17:31.316 - Looking for installed plugin
23:17:32.163 - Detected Vizzed Service Loader
23:17:32.174 - Detected plugin version: 2.41
23:17:32.787 - Initializing Vizzed Service session
23:17:32.898 - Vizzed Service initializion complete
23:17:32.906 - Connected to local Vizzed Service
23:17:33.218 - Downloading Primary game ROM
23:17:33.371 - Found ROM in local cache.
23:17:33.417 - Downloading Required system ROM file #0
23:17:33.446 - Starting file download.
23:17:33.977 - Starting to load game (Phantasy Star IV).
23:17:33.979 - Checking ROM archive file...
23:17:33.982 - Done checking ROM archive...
23:17:33.994 - Extracting ROM archive...
23:17:34.060 - Done extracting ROM archive...
23:17:34.071 - Starting Emulator (genesis).
23:17:34.194 - Emulator Loaded.

Does that help?