Mine is actually a taunt when you kill someone on the game Blitz Brigade: It is get a taste of my lead.

Some I could actually remember from the top of my head would be.

Kingdom Hearts:Got it memorized?

Star Foxo a barrel roll!

pokemon : My rattata is in the top percentage of rattatas!
                 
                 I like shorts they're comfy and easy to wear.

I remember this: It was from marvel ulimate alliance 2: Wolverine said,  " I thought you were here for the red cheeries bub, or something like that"   it was pretty funny in my opinion.

Mine is from Duke Nuke'em. I'VE GOT BALLS OF STEEL.

Honestly, I could quote that whole game. Duke is amazing~

I've got a few. Here goes.

"You can wax on wax off all you like, I'm still... kicking your ass." -Gene (Godhand)

"Even Cielo is greater than you." -Gale (Digital Devil Saga 2)

"Cry me a river, you big wimp." -Allegretto (Eternal Sonata)

All I got for now. I need to brush up on my epic lines dictionary.

 "Did I ever tell you the definition of 'insanity?'" - Vaas, from Far Cry 3.

"SNAKE!?  SNAKE!? SNAAAAAKE!?"  Whenever I hear that, it just makes me chuckle a bit, but I still love it.

I think my favourite line is "My body is ready" from pokemon X and Y.
I know it's not from that game but it is a nice little easter egg in it.

Definitely

Cave Johnson's Lemon speech, best thing ever.

All right, I've been thinking, when life gives you lemons, don't make lemonade! 
Make life take the lemons back! Get Mad!
I don't want your damn lemons! What am I supposed to do with these?
Demand to see life's manager! Make life rue the day it thought it could

give Cave Johnson lemons!
Do you know who I am? I'm the man whose gonna

burn your house down - with the lemons!
I'm gonna get my engineers to invent a combustible lemon that'll burn your house down!

I'm also a fan of this quote also from Cave Johnson.

The lab boys just informed me that I should not have mentioned the control room.
They told me to stop making these pre recorded messages.
That gave me an idea make more pre recorded messages.
I pay the bills here I can talk about the control room all dam day.

And this one from Wheatley

Are they killing you?
They are killing you aren't they.
...
Silently killing you, probably.

All the crap dimentio says
and so I arrive like an unexpected whirlwind at a kindergarten picnic
your blows are like jackhammers wielded by tiny road workers!
yes, you are noticeable by the flailing nubbins you call arms
I recognized you by the festival of hair that dances upon your lips
let us duel like two banjos on a moonlit stoop

that's all I can think of... here's one more from sonic colors
eggman! I AM going to stop you! And I AM going to free those aliens! No copyright law in the universe is gonna stop me!

My favorite line in Star Fox is when Peppy says, "Do a barrel roll!" It's a meme!

these are my favorite qoutes "WHAT I'AM I FIGHTING FOR!?!?"-zero "get a load of this!"-eggman "its no use!"-silver

My favorite line from a game is when Link ' s Fairy is like "HEY! LISTEN!"

"GREAT!" Sonic 06 Silver would be one annoying/funny one.

Or I could use the classic "SNAKE? SNAAAAAAAAKE!" from MGS.

Mine would have to be Dante's line from Devil May Cry 4

"First I whip it out, then I thrust it, with great force. Every angle, it penetrates. Until, with great strength, I ram it in. In the end, we're all satisfied. And you are set free!"

There are so many! Most from Mass Effect. A few of my favourites are:

FemShep to the Reaper On Rannoch: "Tell your friend's we're coming for them". *order's air strike thus killing the Reaper* "Never mind. I'll tell them myself". 

Liara on Virmire: "I don't know which is worse: the geth or all this sand in my...never mind."

FemShep: "How are you getting drunk?"
Tali: "Very carefully. Turian brandy, triple filtered, then introduced into the suit through an emergency induction port."
FemShep: "That's a straw, Tali." 
Tali: "Emergency induction port."

Lara Croft ( Tomb Raider 2013) : "I hate tombs."

One of my favourites is from Final Fantasy VIII:

"What's your department?"

"Guns and women of course."

Glad to see somebody else put a Magus (Chrono Trigger) quote here. Allow me to add another I really liked by him.

Magus "If history is to change, let it change. If the world is to be destroyed, so be it. If my fate is to die, I must simply laugh."


I also can't resist throwing in some lines from Mischief Makers.

Lunar "Through fire, justice is served!"
Taurus "A hero, with shining armor is called!"
Merco "To punish evil forces, I have been charged!"

My favorite quote is from Mother 3, after you visit the chimera lab.

Dr Andonuts- "This is the super duper dryer. It can drain anything, from lakes to Asian beauties!"

I laughed for like 5 minutes XD.
I also like many Wheatley quotes from portal, and pokemon's "I like shorts! They're comfy and easy to wear!"