Ok the standard Nuzlocke rules apply to this, which are:
1. If a Pokemon faints, it is "dead" so you have to release it or box it and never use it again!

2. You can only catch one Pokemon per route/town/city/cave, etc. BUT there's a specie's clause in this challenge so if you encounter a Pokemon you already own or it's evolutionary relative, you may try again, you can do this 3 times before the route becomes void!

3. You must nickname your Pokemon.

4. While you can replace dead Pokemon with Readily available Pokemon, if all 6 in your party faint simultaneously (before you can heal them all) aka a "blacking out" it's game over!

5. Gift Pokemon are allowed!
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Now for the extras:

1. You may only visit 3 Pokemon centers throughout the course of the game, The elite 4 is an exception and has it's own counter of 3 (meaning it's separate from other centers)

2. In order to challenge a Gym/E4/Champ your Pokemon may only be 5 levels above them, any more and you must box them until they're level is balanced. If all Pokemon break rule 2, you may catch 3 "mayday" Pokemon, the standard rules apply, but they can not be trained at all, and Tms are banned (Hms are still OK) After the gym battle, you must box or release them.

3. The item cloning glitch is allowed! But only for Tms and and x-items

4. No legendary Pokemon (obvious)

5. You must catch a Pokemon in route 1, afterwards you have to box or release your starter, the challenge begin until you catch a route 1 Pokemon.

6. You may not evolve your Pokemon for any reason.

7. Hm buddies are only allowed if NONE of your Pokemon can learn a particular Hm. I.E: You get a pidgey and need cut, pidgey cannot learn cut, thus you may catch a rattata to proceed then release it.

8. 1 poke-ball per Pokemon and no master-ball >

9. No daycare!

10. You may not skip trainers for any reason!

11. As always if you're playing on an emulator no save states!

12. You may only save in Pokemon centers.

13. To spice things up,meowth, persain, and payday are banned entirely

14. Mew glitch is banned (as are others like the old man glitch)

15. Repels are banned

16. One hit KO moves are banned

17. Sleep moves are banned as well

18. And if you freeze or sleep an opponent you must start from your last save (so save often )

19. Explosion and self Destruct are allowed, and is the ONLY time you can use a regular revive (max is still banned) and you can not heal or re use the move until you finish the current battle you are on.

20. The safari zone follows the same rules, even if that tauros runs away :'(

If this is too easy for you, pm me rule suggestions, I am always open to them